Upgrading wheel sets can be very-very tricky. Unfortunately they are not
a simple drop in as you would like to think.
First off, modelers generally replace the wheel sets rather than the truck/wheels.
Wheels come in various sizes, 28",33", 36" & 38" but 33" is the most common.
http://www.trains.com/Content/Dynamic/A ... 97xpbs.asp
http://www.nmra.org/beginner/wheelsets.html
Then, you have various axle lengths and this is the gray area. Not all axle lengths are created equal and that depends upon the truck manufacturer that the model car company uses.
For instance, P2K measures 1.008, Intermountain 1.013, KD 1.018. The list goes on. If you don't do your home work, it can be a hit or miss thing as sometimes the axles fit the side frames and sometimes they didn't.
That's because the NMRA specifies minimum dimensions between journals,
no less than 1.038 but there is no maximum.
The rule also specifies maximum axle length of 1.035 but no recommended minimum.
At this point one can get confused. For starters, I would group my cars
according to can manufacturer, Athearn, Atlas etc. Let us know the brands
and we can only suggest a reasonalbe replacement that won't drop out.
The most popular metal wheel replacements are P2K, Intermountain and KD. The intermountains have too much free rolling ability but will get you
to your destination the fastest.