<i>Can anyone guarantee that Acela Express passenger cars would survive slamming into the supports of a highway overpass at speed?</i>
No. Even if anyone did computer simulations to 'prove' it one way or the other, there's simply no database of crash testing to VALIDATE the simulations. Unless you can validate a model, it's pretty useless.
In any case, I'm not aware of any full scale crash testing done on Acelas, and even the FRA's earlier crash tests of Silverliners, etc produced laughable results. It wasn't until they did their CEM design test (ironically of an LIRR M-1), that they started getting anything respectable (and years behind the rest of the world - the French were investigating such techniques in the 60's and 70's - it directly resulted in the wacky look of some French locomotives).
A full scale, instrumented crash test of an Acela would be interesting, but realistically, you'd have to crash most of the fleet to get any real usable results.
<i> The Eschede accident was not a head-on collision (remember, the tire of a driving wheel peeled off and caused the rails to "snakehead" cutting the train in two); and AE passenger cars have open ends—which means that if it met a similar situation, unless everyone's wearing a seat belt, they're going to fly out the open end like the people in the ICE car did and get slammed into the overpass support.</i>
What's more disturbing (IMHO) is that they ever used the wheel design they did - rubber insert wheels had never been used at such high speeds, they were only seen on low speed streetcars and such.
<i>Even worse, the highway bridge collapsed on the rear cars. Think the AE's going to survive that any better than the ICE?</i>
Given what even a 'small' overpass weighs, no train will survive on falling on it. Not even the mighty Acela, which will crush like an aluminum can. Overpasses weigh hundreds of tons, easily.
<i>For the record, the ICE-1 is not a "lightweight"—its passenger cars are similar in weight to the Acela Express, the ICE-1 cars being a mere 11,000 pounds lighter on average. Later versions of ICE are lighter still. (For the nitpickers, ICE-1 is highly relevant here since it was one of the pre-Acela test trains.)</i>
It's no big surprise they're cutting weight - I'm pretty certain the early ICE's had stability issues, on top of ride issues. In any case, lowering the weight results in lower operating and maintenance costs.