I model the St. Lawrence & Atlantic (SLR), the B&M and the MEC. All in the North Country. My current layout I just started features the Groveton area. I use two eras - one with the B&M and Grand Trunk serving Groveton, and also the MEC Beechers Falls Branch, and modern time with SLR and a little NHVT for fun.
When the equipment comes out of storage, and the space for a pike comes available, I'm going to have an international, multi-era, passenger terminal and line operation...
A couple of heavyweight consists...
City of wherever with domes AND American Milemaster....
DB TEE
DB TEN overnight express train
City of Salina M-10000 (thanks Mom!)
Mail and express train...