I really doubt it. It's not just the money, but the fact that if you restore it, you need a place to run it. If you restore a B29, you can fly it pretty much anywhere, but there aren't a lot of lines that could handle a Big Boy and that would be open to the operation of one today. Even back in the day, UP only used them between Ogden and Cheyenne, whereas they used Challengers on all their main lines. No musuem or preservation group would expend the effort to restore to operation a locomotive that would be essentially limited to running on mainlines when there are plenty of smaller, more versatile locomotives out there. It would take the direct support of Union Pacific, but since UP already has the Challenger, which can be used across the system and looks very similar to the Big Boy to the point that the general public probably couldn't tell them apart, there's no incentive for them to restore one.